Synthrom


Sintrom is an anticoagulant that is administered to patients who are at risk of suffering thrombosis or embolism. When taking this drug, the individual must follow rigorous controls with the cardiologist to evaluate how the drug works and the progressive adjustment of the dose.

This medicine is mainly used in those patients who have cardiac arrhythmia since as a consequence of it blood clots can form inside the organ, which would be lethal for the person. It is necessary that patients who use metallic valve prostheses take this medicine to avoid accumulation of blood in the prostheses.

One of the drawbacks of sintrom is that a fixed dose cannot be administered, so continuous evaluations must be carried out to determine the level of blood coagulation. For example, if the dose taken by the patient is very low, the blood coagulates normally, as if he were not taking the treatment, then it is time to increase the dose. But if it is very high, the blood will be highly anticoagulated and there will be a risk of bleeding.

Some patients over 70 years of age tend to have higher plasma concentrations than young people with the same daily dose. Most of the acenocoumarol is found in plasma, 98.7% bound to plasma proteins, especially albumin, and that is where the drug is.

Among the most significant side effects of this anticoagulant is the appearance of bleeding from the nose, gums or urine.